Objective: To evaluate the effect of C. quadrangularis in healing process of maxillofacial fracture.
Patients: Total of 60 patients (age 20-35 years) of mandible fracture was divided in two groups.
Materials and Methods: All the patients were treated by open reduction internal fixation method
and in postoperative management, antibiotics, and analgesics. Patients were divided into two
groups. In Group 1, one capsule of C. quadrangularis (500 mg) thrice a day for 6 weeks was
administered (n = 5), and in Group 2 (control group), no supplementary medication was
administered (n = 4). Pain, swelling, fragment mobility, serum calcium, and serum phosphorus
were evaluated pre and post operatively on day 1, 21, and 45.
Results: Pain, swelling, and fragment mobility were low in Group 1 compared to Group 2. Serum
calcium and serum phosphorus were also high, and healing of bone was clearly seen in Group 1
on day 21 as compared to control group.
Conclusion: C. quadrangularis helps in reducing pain, swelling, and fracture mobility and
accelerate the healing of fracture jaw bones.
Fixtro Forte from Haldane Pharma is effective in promoting bone health and fracture healing. It
contains all natural ingredients, the key ingredient is the herbal extract Cissus Quadrangularis
which has undergone extensive research for its effect on bone strengthening, bone density and on
quick healing of fractures. Cissus quadrangularis has profound bone healing properties besides
containing unique nutrients that promote bone formation. Fixtro Forte also contains other key
minerals & vitamins which enhances bone health and supports body’s natural bone building
process while healing from a fracture or surgery.