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Among joint diseases, Osteoarthritis (OA) is the most prevalent and evolves slowly over decades, manifesting itself in episodes of pain and culminating in the loss of joint function. Inconclusive studies indicate that bone changes can initiate or influence the degradation of cartilage.

Despite many efforts, there is so far no cure for OA, and the treatments available, both pharmacological and non-pharmacological, only act in reducing the symptoms, especially pain, inflammation and immobility.

Collagen hydrolysate (CH) is recognized as safe with minimal adverse effects, whose amino acid composition provides elevated levels of glycine and proline, which accumulate when properly digested, preferentially in cartilage. Both aging and a poor diet can affect the level of collagen in the body.

Collagen hydrolysate has a positive therapeutic role in osteoporosis and osteoarthritis: potentially increasing bone mineral density, having a protective effect on articular cartilage and, primarily, providing symptomatic relief of pain

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